|
|
5alpha-androstane-3alpha,17beta-diol + NAD+ <=> 5alpha-dihydrotestosterone + NADH + H+
|
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
|
–
–
–
–
–
–
–
–
–
|
|
| |
BRENDA:
BR29317
KEGG:
R04330
MetaCyc:
1.1.1.53-RXN;
RXN-12264_WOP
SABIO-RK:
7910
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+
|
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.3.1.20
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
|
K
|
| |
BRENDA:
BS187692;
BS257212-a
KEGG:
R08963
MetaCyc:
RXN-12264
SABIO-RK:
7911
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + NAD+ <=> 5alpha-Androstan-3alpha-ol-17-one + NADH
|
1.1.1.112
indanol dehydrogenase
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
–
–
–
–
|
|
| |
BRENDA:
BS187038;
BS187722-a
SABIO-RK:
11208;
11506
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + NADP+ <=> androsterone + NADPH
|
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62
17beta-estradiol 17-dehydrogenase
1.1.1.64
testosterone 17beta-dehydrogenase (NADP+)
|
–
–
–
–
–
|
|
| |
BRENDA:
BS187722;
BS414158
SABIO-RK:
11553;
14988
|
|
|
|
steroid + reduced_flavodoxin + O2 <=> 5alpha-androstane-3alpha,17beta-diol + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
|
–
|
|
| |
KEGG:
R02131
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + UDP-glucuronate <=> UDP + androstane-3alpha,17beta_diol_O-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
| |
BRENDA:
BS322253
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + UDP-glucuronate <=> UDP + 5alpha-androstane-3alpha,17beta-diol_O-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
| |
BRENDA:
BS322251
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + NADH <=> 5alpha-dihydrotestosterone + NAD+
|
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
|
|
| |
BRENDA:
BS257205-a
|
|
|
|
testosterone + NADPH <=> 5alpha-androstane-3alpha,17beta-diol + androstane-3beta,17beta-diol + 5alpha-dihydrotestosterone
|
1.3.1.22
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
|
–
|
|
| |
BRENDA:
BS258534
|
|
|
|
2 5alpha-dihydrotestosterone + 2 NADPH + 2 H+ <=> 5alpha-Androstane-3beta,17beta-diol + 5alpha-androstane-3alpha,17beta-diol + 2 NADP+
|
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
|
–
|
|
| |
BRENDA:
BS370770
|
|
|
|
(2Z)-2-(5-hydroxy-4,6-dimethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N,N-di(prop-2-en-1-yl)hydrazinecarbothioamide + NADPH+_H+ <=> 5alpha-androstane-3alpha,17beta-diol + NADP+
|
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS451004
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + NADPH <=> 5alpha-dihydrotestosterone + NADP+
|
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
|
–
–
–
|
|
| |
BRENDA:
BS257205
|
|
|
|
5alpha-androstane-3alpha,17beta-diol + NADPH + O2 <=> 5alpha-androstane-3alpha,7alpha,17beta-triol + NADP+ + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
|
| |
BRENDA:
BS408213
|
|
